How do cells and tissue acquire their typical polarity, shape? During development cells proliferate, undergo cell shape changes and rearrange within the tissue to finally generate the stereotypic morphology of the embryo. The tight spatiotemporal control and coordination of these morphogenetic processes is essential for development, and loss of control or coordination of them is a hallmark in the pathology of many diseases.
- intestinal stem cells
- Hematopoietic stem cells